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Rimonabant (Acomplia) diet pill is an anorectic anti-obesity drug. Obese patients taking it 20 mg once daily, show a significant reduction in body weight. Obese patients treated for one year on the highest dose of 20 mg per day shed an average of 19 pounds and lost 3.5 inches of waistline, researchers showed, while 39 percent lost more than one-10th of their body weight.
The dosage for the drug varies from person to person depending upon the body metabolism. The usual recommended dose of Acomplia by doctors is 20 mg daily before breakfast. Acomplia should be swallowed whole with a glass of water, and should not be chewed or crushed.
Early results of two Phase III studies with Sanofi-Synthelabo's Acomplia (March 9, 2004), the first in a new class of therapeutics called Selective CB1 Blockers, indicate that overweight/obese patients with untreated dyslipidemia (high triglycerides and/or high total cholesterol/HDL cholesterol ratio) lost weight in one year while improving their lipid and glucose profiles, and that smokers who had previously unsuccessfully tried to quit smoking, were able to quit in 10 weeks without post cessation weight gain.
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