Voltaren

diclofenac sodium

Diclofenac belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs) that are used for the treatment of mild to moderate pain, fever, and inflammation. Other members of this class include ibuprofen, indomethacin, nabumetone, naproxen and several others. NSAIDs work by reducing the production of prostaglandins, chemicals that cause pain, fever and inflammation. NSAIDs block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower production of prostaglandins. As a consequence, inflammation, pain and fever are reduced.

This medicine is used for musculoskeletal complaints, especially arthritis (rheumatoid arthritis, osteoarthritis, spondylarthritis, ankylosing spondylitis), gout attacks, and pain management in case of kidney stones and gallstones. An additional indication is the treatment of acute migraines. Diclofenac is used commonly to treat mild to moderate post-operative or post-traumatic pain, particular when inflammation is also present, and is effective against menstrual pain.

Voltaren is currently the eighth largest-selling drug and the most frequently used NSAID in the world. Diclofenac, is a potent inhibitor of cyclooxygenase enzyme activity, and may also interact with the lipoxygenase enzyme pathway, and with the release and reuptake of arachidonic acid. Diclofenac is almost completely absorbed, highly protein-bound, penetrates well into synovial fluid, and is extensively metabolized.

How to use
Take this medication with food, milk, or antacids to prevent stomach upset. This medication is most effective in relieving menstrual pain if taken at the earliest sign of pain. Take this medication with 6 to 8 ounces (180-240ml) of water. Do not lie down for at least 30 minutes after taking this drug.

Voltaren Dosage
- Osteoarthritis: 100-150 mg a day, divided into smaller doses of 50 mg 2 or 3 times a day
- Rheumatoid Arthritis: 100-200 mg a day, divided into smaller doses of 50 mg 3 to 4 times a day
- Ankylosing Spondylitis: 100-125 mg a day, divided into smaller doses of 25 mg 4 times a day
- Pain and menstrual discomfort: 50 mg every 8 hours as needed

Side effects
If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Voltaren. Side effects may include: abdominal bleeding, abdominal pain or cramps, abdominal swelling, anemia, blood clotting problems, constipation, diarrhea, dizziness, fluid retention, gas, headache, heartburn, indigestion, itching, nausea, peptic ulcers, rash, ringing in the ears, vomiting.

Do not drink alcohol while taking diclofenac. Alcohol can increase the risk of stomach bleeding caused by diclofenac. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Diclofenac can make your skin more sensitive to sunlight and sunburn may result.