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Generic name (substance): Spironolactone.
Common brand, trade, commercial denominations: Aldactone, Novo-Spiroton, Aldactazide, Spiractin, Spirotone, Berlactone, Abbolactone, Acelat, Aldace, Aldactide, Alderon, Aldopur, Almatol, Altex, Aquareduct, Deverol, Diatensec, Dira, Duraspiron, Euteberol, Lacalmin, Lacdene, Laractone, Lasilactone, Melarcon, Nefurofan, Osiren, Osyrol, Sagisal, Sincomen, Spiresis, Spiretic, Spiridon, Spiroctan, Spiroctanie, Spiroderm, Spirolactone, Spirolakton, Spirolang, Spirolone, Spirone, Spironocompren, Spironolactonum, Spironolattone, Sprioderm, Supra-puren, Suracton, Uractone, Urusonin, Verospiron, Verospirone, Xenalon.
Manufacturers: Ali Raif, Mylan Pharmaceuticals Inc., Rugby, Actavis, URL, Actavis U.S. (Purepac Pharmaceutical Company), United Research Laboratories/Mutual Pharmaceutical Company, Sandoz Inc., Greenstone, Qualitest Pharmaceuticals, Schein, Pfizer U.S. Pharmaceuticals Group, Searle, Pharmacia Corp.
Systematic (IUPAC) name: 7a-Acetylthio-3-oxo-17a-pregn-4-ene-21,17-carbolactone
Molecular formula: C24H32O4S
Molecular mass: 416.574 g/mol
Metabolism: Hepatic
Half life: 10 minutes
Excretion: Urine, bile
CAS number: 52-01-7
Route of Administration: Oral
Drug class: Antiandrogen
Chemical class: Aldosterone antagonist
Therapeutic class: Antihypertensive, Potassium-sparing diuretic
Pharmacologic class: Aldosterone inhibitor
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