The dose of inhaled fluticasone and salmeterol will be different for different patients. Follow your doctor's orders or the direction on the label. The following information includes only the average doses of inhaled fluticasone and salmeterol. If your dose is different, do not change it unless your doctor tells you to do so.

For bronchial asthma:
Adults and children 4 years of age and older: One inhalation twice a day, about 12 hours apart.
Children up to 4 years of age: Use and dose must be determined by your doctor.

For chronic obstructive pulmonary disease with chronic bronchitis:
Adults: One inhalation (250/50) twice a day, about 12 hour apart.
Children: Use and dose must be determined by your doctor.