Retin-A (tretinoin) cream is intended for the treatment of acne. This drug works by replacing older skin with newer skin removing the cells that are no longer needed. In the skin, it affects the depletion and dispersion of melanin as well as thickening and strengthening the tissues. Retin A increases blood vessel development and cell nutrition, decreases clogged pores and makes cells divide faster.

Retin-A Cream should be applied once a day, before retiring, to the skin where acne lesions appear, using enough to cover the entire affected area lightly.

During the early weeks of therapy, an apparent exacerbation of inflammatory lesions may occur. This is due to the action of the medication in deep, previously unseen lesions and should not be considered a reason to discontinue therapy.

Therapeutic results should be noticed after two to three weeks, but more than 6 weeks of therapy may be required before definite beneficial effects are seen. Once the acne lesions have responded satisfactorily, it may be possible to maintain the improvement with less frequent applications, or other dosage forms.