Acomplia
rimonabant
Acomplia is used for treating obesity and is first in a new class of therapeutic agents called cannabinoid -1 receptor blocker. Acomplia is efficiently used for curing obesity and also other related conditions.
Drug Action
Acomplia selectively blocks the receptors of cannabinoid-1 which is found in the brain and other peripheral organs of the body like adipose tissue, liver, gastro intestinal tract, muscle 1, etc, which are responsible for lipid and glucose metabolism. Acomplia functions by switching off the main circuit from the brain that sends signals for hunger. The blocking of cannabinoid receptors by Acomplia decreases the over activity of endocannabinoid system 2, 3 termed as EC-2, 3. EC-2, 3 contains receptors like CB1, receptors that plays an important role in body weight regulation, energy balance, metabolism of glucose and lipid, etc.
Drug Uses
Acomplia is mainly used for overweight patients who suffer type 2 diabetes and abnormal fat deposits in the blood. Acomplia is also used for preventing cardio vascular diseases. Persons having waist lines 108cms men and 88cms female, especially benefit from Acomplia.
Other Acomplia Benefits
Acomplia is also useful in patients who wish to stop smoking. However, Sanofi Aventis pharmacy issued non approval for the use of Acomplia for smoke cessation.
Acomplia Side Effects
Some of the side effects of Acomplia include:
About 19% of the people who took Acomplia and about 13% of the people who took placebo were forced to leave the trial on account of the drug side effects.
